Single-step kinase inhibitor screening using a peptide-modified gold nanoparticle platform.
نویسندگان
چکیده
Two complementary formats for kinase inhibitor screening are presented in which peptide-modified gold nanoparticles are enzymatically phosphorylated and rapidly aggregate on a surface or in solution by action of phosphospecific antibodies. The simple and rapid colourimetric response of the assays makes them an attractive approach for drug-screening applications.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 47 8 شماره
صفحات -
تاریخ انتشار 2011